Peptid receptor radionuklid terápia neuroendokrin daganatokban
Cikk címe: Peptid receptor radionuklid terápia neuroendokrin daganatokban
Szerzők: Dr. Dabasi Gabriella
Intézmények: Semmelweis Egyetem Általános Orvostudományi Kar Nukleáris Medicina Tanszék
Évfolyam: XVI. évfolyam
Lapszám: 2017. / 05. lapszám
Oldal: 44-47
Rovat: KÉPALKOTÓ DIAGNOSZTIKA
Alrovat: TERANOSZTIKA
Absztrakt:
A peptid receptor radionuklid terápia egy új és ígéretes terápiás módszer a neuroendokrin daganatok kezelésében. Több mint két évtizede alkalmazzák inoperábilis, illetve áttéteket adó gastro-pancreatikus daganatokban és egyéb neuroendokrin tumorokban. A betegek infúzióban 90Ittrium vagy 177Lutécium szomatosztatin analógot kapnak. A terápiás válasz függ a daganat típusától és az alkalmazott izotóptól. Az objektív terápiás válasz, az általános túlélés és a progresszió mentes túlélés szignifikáns mértékben nő az irodalmi adatok szerint. Magyarországon ez a kezelés még nem elérhető, bevezetését tervezzük. A közleményben kitekintést szeretnék adni a legújabb eredményekre, annak reményében, hogy a PRRT a közeljövőben itthon is megvalósítható lesz.
Abstract:
Peptide Receptor Radionuclide Therapy (PRRT) is a new and promising therapy for patients with neuroendocrine tumours. PRRT is utilized for more than two decades in the treatment of metastatic or inoperable gastropancreatic neouroendocrin neoplasms (NENs) or other neuroendocrine tumours (NETs). This therapy involves an infusion of somatostatin analogues labelled with 90Yttrium or 177Lutecium. Response rate may vary between type of tumour and radionuclide. The objective response rate, the overall survival and progression free survival increase significantly according to the literature. This therapy is not available in Hungary. In this publication author gives an outlook on the newest achievements in the hope that in the near future it will be implemented in Hungary as well.
XVI. évfolyam
2017. / 05. lapszám / Május
| Szerző | Intézmény |
|---|---|
| Dr. Dabasi Gabriella | Semmelweis Egyetem Általános Orvostudományi Kar Nukleáris Medicina Tanszék |
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